drug induced exfoliative dermatitis

Su SC, Hung SI, Fan WL, Dao RL, Chung WH. These molecules may play a role in amplifying the immune response and in increasing the release of other toxic metabolites from inflammatory cells [48]. Generalized. official website and that any information you provide is encrypted 2013;27(5):65961. Oliveira L, Zucoloto S. Erythema multiforme minor: a revision. Allergy. Ethambutol Induced Exfoliative Dermatitis. Stern RS. Herpes simplex virus (HSV) 1 and 2 are the main triggers in young adults (>80% of cases), followed by Epstein-Barr virus (EBV), and Mycoplasma pneumonia [5558]. Smith SD, et al. It is important to take into consideration the mechanism of action of the different drugs in the pathogenesis of ED [104]. 2014;70(3):53948. Mardani M, Mardani S, Asadi Kani Z, Hakamifard A. Dermatol Ther. exfoliative dermatitis. Google Scholar. 2014;81(1):1521. Huang SH, et al. The time interval between the appearance of exfoliative dermatitis and the appearance of cutaneous T-cell lymphoma lesions can vary from months to years or even decades. It is recommended to use 1.5mg/kg hydrocortisone. Case Rep Dermatol Med. These studies have confirmed an association between carbamazepine-induced SJS/TEN with HLA-B*1502 allele among Han Chinese [27], carbamazepine and HLA-A*3101 and HLA-B*1511 [16], phenytoin and HLA-B*1502 [28], allopurinol and HLA-B*5801 [29]. Drug Rashes | Johns Hopkins Medicine Br J Dermatol. 2013;27(3):35664. Clinical features; Delayed type hypersensitivity; Drug hypersensitivity; Erythema multiforme; Exfoliative dermatitis; Lyells syndrome; Pathogenesis; StevensJohnson syndrome; Therapy; Toxic epidermal necrolysis. Both DRESS and SJS may have increased liver enzymes and hepatitis, but they occur in only 10% of cases of SJS compared to 80% of DRESS. Abe J, et al. Article Tohyama M, et al. The erythrodermic form of mycosis fungoides and the Szary syndrome may also be difficult to distinguish from benign erythroderma. Dupixent DUPILUMAB 200 mg/1.14mL sanofi-aventis U.S. LLC It often precedes or is associated with exfoliation (skin peeling off in scales or layers), when it may also be known as exfoliative dermatitis (ED). Furosemide or ethacrynic acid may be required to maintain an adequate urinary output [90]. Bookshelf (PDF) DiHS/DRESS syndrome induced by second-line treatment for The induction dosage in EMM is usually 1mg/kg/day that should be maintained until a complete control of the skin is obtained. Moreover Mawson A and colleagues hypothesized that the efficacy of plasmapheresis is able to reduce serum level of vitamin A.

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